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Papers of the Week

2021 May 30

Paediatr Anaesth

An assessment of opioids on respiratory depression in children with and without obstructive sleep apnea.


Adler AC, Chandrakantan A, Nathanson BH, von Ungern-Sternberg BS
Paediatr Anaesth. 2021 May 30.
PMID: 34053151.


Obstructive sleep apnea (OSA) is a risk factor for respiratory depression following opioid administration as well as opioid-induced hyperalgesia. Little is known on how OSA status is associated with central ventilatory depression in pediatric surgical patients given a single dose of fentanyl.