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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Epidural Naloxone Attenuates Fentanyl Induced PONV in Patients Undergoing Lower Limb Orthopaedic Surgeries. a Prospective Randomized Double-Blind Comparative Study.

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2020 Jul


Rom J Anaesth Intensive Care


http://www.ncbi.nlm.nih.gov/pubmed/34056121?dopt=Abstract


27


1

Epidural Naloxone Attenuates Fentanyl Induced PONV in Patients Undergoing Lower Limb Orthopaedic Surgeries. a Prospective Randomized Double-Blind Comparative Study.

Authors

Epidural Naloxone Attenuates Fentanyl Induced PONV in Patients Undergoing Lower Limb Orthopaedic Surgeries. a Prospective Randomized Double-Blind Comparative Study.
Nimeeliya Z, Derlin T, Kundil Alungal S R, Kanjirathummoottil G
Rom J Anaesth Intensive Care. 2020 Jul; 27(1):23-28.
PMID: 34056121.

Abstract

Epidural administration of opioids with local anaesthetics is a popular choice for perioperative pain relief. But opioid induced side effects limit their use for postoperative analgesia. Hence, this study was designed to evaluate the effectiveness of epidural naloxone, an opioid receptor antagonist, in reducing PONV in patients receiving epidural fentanyl.
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