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Papers of the Week

Papers: 29 May 2021 - 4 Jun 2021


Human Studies

2021 May 26

Life Sci

Nociceptive stress interferes with neural processing of cognitive stimuli in Gulf War Veterans with chronic musculoskeletal pain.


Lindheimer JB, Stegner AJ, Van Riper SM, Ninneman JV, Ellingson LE, Cook DB
Life Sci. 2021 May 26:119653.
PMID: 34051215.


Disrupted cognition and chronic musculoskeletal pain (CMP) are prevalent experiences among Gulf War Veterans (GWV). A negative association between CMP and cognition (i.e., chronic pain-related cognitive interference) has been observed in some chronic pain populations but has not been evaluated in GWV. Additional research suggests that disrupted cognition in GWV with CMP may be exacerbated by stressing the nociceptive system. Therefore, we compared cognitive performance and related neural activity between CMP and healthy control (CO) GWV in the absence and presence of experimental pain.