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Papers of the Week

Papers: 22 May 2021 - 28 May 2021

Animal Studies, Pharmacology/Drug Development

2021 May 20

Osteoarthritis Cartilage

A novel placental tissue biologic, PTP-001, inhibits inflammatory and catabolic responses in vitro and prevents pain and cartilage degeneration in a rat model of osteoarthritis.


Flannery CR, Seaman SA, Buddin KE, Nasert MA, Semler EJ, Kelley KL, Long M, Favret J, Pavesio A, Loeser RF
Osteoarthritis Cartilage. 2021 May 20.
PMID: 34023528.


Characterization of a novel human placental tissue-derived biologic, PTP-001, which is in development as a candidate therapeutic for the treatment of osteoarthritis symptoms and pathophysiology.