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Papers of the Week


Papers: 22 May 2021 - 28 May 2021


Animal Studies, Pharmacology/Drug Development


2021 May 20


Osteoarthritis Cartilage

A novel placental tissue biologic, PTP-001, inhibits inflammatory and catabolic responses in vitro and prevents pain and cartilage degeneration in a rat model of osteoarthritis.

Authors

Flannery CR, Seaman SA, Buddin KE, Nasert MA, Semler EJ, Kelley KL, Long M, Favret J, Pavesio A, Loeser RF
Osteoarthritis Cartilage. 2021 May 20.
PMID: 34023528.

Abstract

Characterization of a novel human placental tissue-derived biologic, PTP-001, which is in development as a candidate therapeutic for the treatment of osteoarthritis symptoms and pathophysiology.