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Papers of the Week

2021 May 13


Systematic literature review and network Meta-analysis of sulodexide and other drugs in chronic venous disease.


Pompilio G, Nicolaides A, Kakkos SK, Integlia D
Phlebology. 2021 May 13:2683555211015020.
PMID: 33983078.


To assess the clinical efficacy of sulodexide, including a comparison with venoactive drugs (VAD) (micronized purified flavonoid fraction, MPFF; hydroxy-ethyl-rutosides, HR; calcium dobesilate;Ruscus extract combined with hesperidin methyl chalcone and vitamin C, Ruscus+HMC+VitC; horse chestnut seed extract, HCSE) and pentoxifylline in patients with chronic venous disease.