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Papers of the Week

Papers: 8 May 2021 - 14 May 2021

Human Studies

2021 May 10

BMC Musculoskelet Disord



Temporal summation of mechanical pain prospectively predicts movement-evoked pain severity in adults with chronic low back pain.


Overstreet DS, Michl AN, Penn TM, Rumble DD, Aroke EN, Sims AM, King AL, Hasan FN, Quinn TL, Long LD, Sorge RE, Goodin BR
BMC Musculoskelet Disord. 2021 May 10; 22(1):429.
PMID: 33971876.


Biopsychosocial factors above and beyond pathoanatomical changes likely contribute to the severity of chronic low back pain. A pro-nociceptive endogenous pain modulatory balance (↓inhibition and ↑facilitation) may be an important contributor to chronic low back pain severity and physical function; however, additional research is needed to address this possibility. The objective of this study was to determine whether quantitative sensory tests of endogenous pain inhibition and facilitation prospectively predict movement-evoked pain and cLBP severity self-reported on a validated questionnaire.