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Papers of the Week

Papers: 8 May 2021 - 14 May 2021

Pharmacology/Drug Development

2021 May 10

Curr Pain Headache Rep



Recent Advances in Peripheral Opioid Receptor Therapeutics.


Seth R, Kuppalli SS, Nadav D, Chen G, Gulati A
Curr Pain Headache Rep. 2021 May 10; 25(7):46.
PMID: 33970352.


Although opioids are excellent analgesics, they are associated with severe short- and long-term side effects that are especially concerning for the treatment of chronic pain. Peripherally acting opioid receptor agonists promise to mitigate the more serious centrally mediated side effects of opioids, and the goal of this paper is to identify and elaborate on recent advances in these peripheral opioid receptor therapeutics.