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Papers of the Week

2021 Feb

Res Pharm Sci



Preparation and characterization of ethylcellulose microspheres for sustained-release of pregabalin.


Yasin H, Al-Taani B, Salem M S
Res Pharm Sci. 2021 Feb; 16(1):1-15.
PMID: 33953770.


Pregabalin is used in the treatment of epilepsy, chronic pain, and other psychological disorders. Preparation of pregabalin in the sustained-release formulation will enhance patient compliance and reduce the incidence of side effects. The aim of this study was to prepare sustained-release microspheres for pregabalin utilizing ethylcellulose and evaluate the processing factors that influence the fabrication and the performance of the prepared microspheres.