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Papers of the Week


2021


J Healthc Eng


2021

Text Mining-Based Drug Discovery in Osteoarthritis.

Authors

Yu R-G, Zhang J-Y, Liu Z-T, Zhuo Y-G, Wang H-Y, Ye J, Liu N, Zhang Y-Y
J Healthc Eng. 2021; 2021:6674744.
PMID: 33953899.

Abstract

Osteoarthritis (OA) is a chronic and degenerative joint disease, which causes stiffness, pain, and decreased function. At the early stage of OA, nonsteroidal anti-inflammatory drugs (NSAIDs) are considered the first-line treatment. However, the efficacy and utility of available drug therapies are limited. We aim to use bioinformatics to identify potential genes and drugs associated with OA.