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Papers of the Week

2021 May 06

Fluids Barriers CNS



Serial Tap Test of patients with idiopathic normal pressure hydrocephalus: impact on cognitive function and its meaning.


da Rocha S F B, Kowacs P A, de Souza R K M, Pedro M K F, Ramina R, Teive H GA
Fluids Barriers CNS. 2021 May 06; 18(1):22.
PMID: 33957939.


Idiopathic normal pressure hydrocephalus (INPH) is characterized by gait disturbance, urinary incontinence and cognitive decline. Symptoms are potentially reversible and treatment is based on cerebrospinal fluid shunting. The tap test (TT) is used to identify patients that will benefit from surgery. This procedure consists of the withdrawal of 20 to 50 mL of cerebrospinal fluid (CSF) through a lumbar puncture (LP) after which the symptoms of the triad are tested. Improvement in the quality and speed of gait are already recognized but cognitive improvement depends on several factors such as tests used, the time elapsed after LP for re-testing, and the number of punctures. Serial punctures may trigger similar conditions as external lumbar drainage (ELD) to the organism.