I am a
Home I AM A Search Login

Papers of the Week

Papers: 8 May 2021 - 14 May 2021

Animal Studies

2021 May 03

Endocrinol Diabetes Nutr

miR-125a-5p in astrocytes attenuates peripheral neuropathy in type 2 diabetic mice through targeting TRAF6.


Kasimu A, Apizi X, Talifujiang D, Ma X, Fang L, Zhou X
Endocrinol Diabetes Nutr. 2021 May 03.
PMID: 33958320.


Elimination or blocking of astrocytes could ameliorate neuropathic pain in animal models. MiR-125a-5p, expressed in astrocyte derived extracellular vesicles, could mediate astrocyte function to regulate neuron communication. However, the role of miR-125a-5p in DPN (diabetic peripheral neuropathy) remains elusive.