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Papers of the Week

2021 May 07

Curr Pain Headache Rep



Flavonoids in the Treatment of Neuropathic Pain.


Rao PN, Mainkar O, Bansal N, Rakesh N, Haffey P, Urits I, Orhurhu V, Kaye AD, Urman RD, Gulati A, Jones M
Curr Pain Headache Rep. 2021 May 07; 25(7):43.
PMID: 33961144.


Chronic pain continues to present a large burden to the US healthcare system. Neuropathic pain, a common class of chronic pain, remains particularly difficult to treat despite extensive research efforts. Current pharmacologic regimens exert limited efficacy and wide, potentially dangerous side effect profiles. This review provides a comprehensive, preclinical evaluation of the literature regarding the role of flavonoids in the treatment of neuropathic pain.