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Papers of the Week
Intracerebroventricular injection of propranolol blocked analgesic and neuroprotective effects of resveratrol following L spinal nerve ligation in rat.
Abstract
Resveratrol as a natural polyphenolic agent can alleviate neuropathic pain symptoms. The mechanism of analgesic activity of resveratrol is far from clear. The current study examine whether analgesic activity of resveratrol is mediated by its neuroprotective and anti-oxidant activity in the neuropathic pain. We further examine whether analgesic activity of resveratrol is mediated by β-adrenoceptors in the brain.