I am a
Home I AM A Search Login

Papers of the Week

Papers: 1 May 2021 - 7 May 2021

2021 May 05




Human cells and networks of pain: Transforming pain target identification and therapeutic development.


Renthal W, Chamessian A, Curatolo M, Davidson S, Burton M, Dib-Hajj S, Dougherty PM, Ebert AD, Gereau RW, Ghetti A, Gold MS, Hoben G, Menichella D M, Mercier P, Ray WZ, Salvemini D, Seal RP, Waxman S, Woolf CJ, Stucky CL, et al.
Neuron. 2021 May 05; 109(9):1426-1429.
PMID: 33957072.


Chronic pain is a disabling disease with limited treatment options. While animal models have revealed important aspects of pain neurobiology, therapeutic translation of this knowledge requires our understanding of these cells and networks of pain in humans. We propose a multi-institutional collaboration to rigorously and ethically address this challenge.