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Papers of the Week

Papers: 1 May 2021 - 7 May 2021

Human Studies


2021 May 02

Ann Clin Transl Neurol

Plasma calcitonin gene-related peptide (CGRP) in migraine and endometriosis during the menstrual cycle.


Raffaelli B, Overeem L H, Mecklenburg J, Hofacker M D, Knoth H, Nowak C P, Neeb L, Ebert A D, Sehouli J, Mechsner S, Reuter U
Ann Clin Transl Neurol. 2021 May 02.
PMID: 33934575.


Migraine, endometriosis, and the comorbidity of both are frequent pain disorders of special relevance for women. The neuropeptide calcitonin gene-related peptide (CGRP) is critically involved in migraine, and circumstantial evidence suggests a role in endometriosis. We assessed CGRP levels at different times of menstrual cycle in four groups: healthy women, women with migraine or endometriosis and with the comorbidity of both.