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Papers of the Week

2021 Apr 28

Vision (Basel)



Visual Perception in Migraine: A Narrative Review.


Hadjikhani N, Vincent M
Vision (Basel). 2021 Apr 28; 5(2).
PMID: 33924855.


Migraine, the most frequent neurological ailment, affects visual processing during and between attacks. Most visual disturbances associated with migraine can be explained by increased neural hyperexcitability, as suggested by clinical, physiological and neuroimaging evidence. Here, we review how simple (e.g., patterns, color) visual functions can be affected in patients with migraine, describe the different complex manifestations of the so-called Alice in Wonderland Syndrome, and discuss how visual stimuli can trigger migraine attacks. We also reinforce the importance of a thorough, proactive examination of visual function in people with migraine.