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Papers of the Week

Papers: 1 May 2021 - 7 May 2021

Human Studies

2021 Apr 29

Ann Rheum Dis

Genome-wide association study identifies locus as associated with chronic widespread musculoskeletal pain.


Rahman M S, Winsvold BS, Chavez Chavez SO, Børte S, Tsepilov YA, Sharapov S Z, Aulchenko YS, Hagen K, Fors EA, Hveem K, Zwart J A, van Meurs JB, Freidin MB, Williams FMK
Ann Rheum Dis. 2021 Apr 29.
PMID: 33926923.


Chronic widespread musculoskeletal pain (CWP) is a symptom of fibromyalgia and a complex trait with poorly understood pathogenesis. CWP is heritable (48%-54%), but its genetic architecture is unknown and candidate gene studies have produced inconsistent results. We conducted a genome-wide association study to get insight into the genetic background of CWP.