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Papers of the Week

Papers: 24 Apr 2021 - 30 Apr 2021


Human Studies

2021 Apr 28

JMIR Res Protoc



A Live Video Program to Prevent Chronic Pain and Disability in At-Risk Adults With Acute Orthopedic Injuries (Toolkit for Optimal Recovery): Protocol for a Multisite Feasibility Study.


Vranceanu A-M, Bakhshaie J, Reichman M, Doorley J, Elwy RA, Jacobs C, Chen N, Esposito J, Laverty D, Matuszewski PE, Fatehi A, Bowers LC, Harris M, Ring D
JMIR Res Protoc. 2021 Apr 28; 10(4):e28155.
PMID: 33908886.


Despite the pivotal role of psychosocial factors in pain and disability after orthopedic injury, there are no evidence-based preventive interventions targeting psychosocial factors in patients with acute orthopedic injuries. We developed the first mind-body intervention focused on optimizing recovery and improving pain and disability in patients with acute orthopedic injuries who exhibit high levels of catastrophic thinking about pain and/or pain anxiety (Toolkit for Optimal Recovery [TOR] after orthopedic injury). In a pilot single-site randomized controlled trial (RCT), the TOR met a priori set benchmarks for feasibility, acceptability, and satisfaction. The next step in developing TOR is to conduct a multisite feasibility RCT to set the stage for a scientifically rigorous hybrid efficacy-effectiveness trial.