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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / The Inclusion of Tolfenamic Acid into Cyclodextrins Stimulated by Microenvironmental pH Modification as a Way to Increase the Anti-Migraine Effect.

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2021


J Pain Res


http://www.ncbi.nlm.nih.gov/pubmed/33883930?dopt=Abstract


14

The Inclusion of Tolfenamic Acid into Cyclodextrins Stimulated by Microenvironmental pH Modification as a Way to Increase the Anti-Migraine Effect.

Authors

The Inclusion of Tolfenamic Acid into Cyclodextrins Stimulated by Microenvironmental pH Modification as a Way to Increase the Anti-Migraine Effect.
Stasiłowicz A, Tykarska E, Rosiak N, Sałat K, Furgała-Wojas A, Plech T, Lewandowska K, Pikosz K, Pawłowicz K, Cielecka-Piontek J
J Pain Res. 2021; 14:981-992.
PMID: 33883930.

Abstract

The poorly soluble nonsteroidal anti-inflammatory drug (NSAID), tolfenamic acid (TA), was studied to maximize its solubility, permeability through biological membranes, and pharmacological activity.
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