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Papers of the Week

2021 Mar-Apr

Endosc Ultrasound



EUS and secretin endoscopic pancreatic function test predict evolution to overt structural changes of chronic pancreatitis in patients with nondiagnostic baseline imaging.


Monachese M, Lee PJ, Harris K, Jang S, Bhatt A, Chahal P, Lopez R, Stevens T
Endosc Ultrasound. 2021 Mar-Apr; 10(2):116-123.
PMID: 33885007.


The accuracy of EUS and endoscopic pancreatic function test (ePFT) for diagnosis of early or minimal-change chronic pancreatitis (MCCP) is poorly understood. We hypothesized that the natural history of the disease may be used as a "gold standard" to assess the ability of EUS and ePFT to predict the eventual development of overt chronic pancreatitis (CP) changes on computed tomography/magnetic resonance cholangiopancreatography (CT/MRCP). The aim of the study was to determine the ability of EUS and ePFT to predict disease progression in patients with suspected MCCP who had nondiagnostic baseline imaging.