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Papers of the Week


2021 Apr 23


Prenat Diagn

Fetally-injected drugs for immobilization and analgesia do not modify fetal brain development in a rabbit model.

Authors

Van der Veeken L, Inversetti A, Galgano A, Bleeser T, Papastefanou I, van de Merwe J, Rex S, Deprest J
Prenat Diagn. 2021 Apr 23.
PMID: 33892522.

Abstract

During fetal surgery, fetuses receive medication (atropine-fentanyl-curare) to prevent fetal pain, movement and bradycardia. Although essential there has been no detailed review of potential side effects. Herein we aimed to assess the effects of this medication cocktail on fetal brain development in a rabbit model.