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Papers of the Week

2021 Apr 08

Vet Dermatol

Onset and duration of action of lokivetmab in a canine model of IL-31 induced pruritus.


Fleck TJ, Norris LR, Mahabir S, Walters RR, Martinon O, Dunham SA, Gonzales AJ
Vet Dermatol. 2021 Apr 08.
PMID: 33830571.


Interleukin (IL)-31 is a cytokine involved in allergic inflammation which induces pruritus across species including dogs. Using recombinant canine IL-31 we have developed a model of pruritus in the dog to evaluate onset of action and duration of effect of therapeutic drugs.