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Papers of the Week

2021 Mar 29

Clin Orthop Relat Res

Plasma D-dimer Does Not Anticipate the Fate of Reimplantation in Two-stage Exchange Arthroplasty for Periprosthetic Joint Infection: A Preliminary Investigation.


Pannu TS, Villa JM, Engh C, Patel A, Levine BR, Piuzzi NS, Higuera CA, Riesgo AM
Clin Orthop Relat Res. 2021 Mar 29.
PMID: 33830953.


Inflammatory markers such as the erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels have always been a part of the diagnostic criteria for periprosthetic joint infection (PJI), but they perform poorly anticipating the outcome of reimplantation. D-dimer has been reported in a small series as a potential marker to measure infection control after single-stage revisions to treat PJI. Nonetheless, its use to confirm infection control and decide the proper timing of reimplantation remains uncertain.