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Papers of the Week

2021 Mar 24


Randomized Study of Metoclopramide Plus Diphenhydramine for Acute Posttraumatic Headache.


Friedman BW, Irizarry E, Cain D, Caradonna A, Minen MT, Solorzano C, Zias E, Zybert D, McGregor M, Bijur PE, Gallagher JE
Neurology. 2021 Mar 24.
PMID: 33762421.


To determine whether intravenous (IV) metoclopramide 20mg + diphenhydramine 25mg (M+D) was more efficacious than IV placebo for acute moderate or severe post-traumatic headache in the emergency room.