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Papers of the Week

2021 Jan 27

J Chest Surg

Unilateral Giant Bullae: Pulmonary Placental Transmogrification Should Be Kept in Mind.


Hamad A-MM, Nosseir MM, Alorainy SM
J Chest Surg. 2021 Jan 27.
PMID: 33767031.


Placental transmogrification is a peculiar clinical entity of the lung of uncertain etiology. We report 2 cases of pulmonary placental transmogrification in 2 patients of different nationalities. Both of them had no history of smoking or chronic lung disease. The main presentations were dyspnea and chest pain. Radiologic studies showed a unilateral giant bulla in both patients; additional pneumothorax was present in only 1patient. They underwent surgical bullectomy. Histopathologic studies revealed the presence of intracystic placenta-like villous structures and a diagnosis of placental transmogrification was made. Placental transmogrification should be considered in cases of unilateral bullae.