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Papers of the Week


2021 Mar


Kidney Int Rep


6


3

Efficacy and Safety of a Novel Nicotinamide Modified-Release Formulation in the Treatment of Refractory Hyperphosphatemia in Patients Receiving Hemodialysis-A Randomized Clinical Trial.

Authors

Ketteler M, Wiecek A, Rosenkranz AR, Pasch A, Rekowski J, Hellmann B, Karus M, Ammer R
Kidney Int Rep. 2021 Mar; 6(3):594-604.
PMID: 33732974.

Abstract

Despite widespread use of phosphate binders (PBs), phosphate control is insufficient in many hemodialysis patients. Preliminary clinical observations suggest that nicotinamide may act synergistically with PBs to improve phosphate control.