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Papers of the Week

2021 Mar 09

Br J Anaesth

Opioids and premature biochemical recurrence of prostate cancer: a randomised prospective clinical trial.


Rangel FP, Auler JOC, Carmona MJC, Cordeiro MD, Nahas WC, Coelho RF, Simões CM
Br J Anaesth. 2021 Mar 09.
PMID: 33712224.


Prostate cancer is one of the most prevalent neoplasms in male patients, and surgery is the main treatment. Opioids can have immune modulating effects, but their relation to cancer recurrence is unclear. We evaluated whether opioids used during prostatectomy can affect biochemical recurrence-free survival.