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The writing group of formulated the consensus by organizing face-to-face national multi-disciplinary expert meetings for 3 times, combining theoretical and practical experience, and drawing lessons from application of mixed inhalation of nitrous oxide and oxygen sedation and analgesia technology in other disciplines at home and abroad. The consensus carried on the detailed description on the indications, contraindications, possible side effects and corresponding first aid measures, application process, operation conditions, and training of the techndogy in burn surgery,and formulated the relevant solutions.