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Papers of the Week

2021 Mar 10

Pediatr Crit Care Med

Prediction of Nociception in Children Using the Nociceptive Flexion Reflex Threshold and the Bispectral Index-A Prospective Exploratory Observational Study.


Mauritz MD, Uhlenberg F, Bashir-Elahi D, Werther T, Gottschalk U, Ebenebe C U, Bergers M, Giordano V, Vettorazzi E, Singer D, Deindl P
Pediatr Crit Care Med. 2021 Mar 10.
PMID: 33710075.


The prediction of patient responses to potentially painful stimuli remains a challenge in PICUs. We investigated the ability of the paintracker analgesia monitor (Dolosys GmbH, Berlin, Germany) measuring the nociceptive flexion reflex threshold, the cerebral sedation monitor bispectral index (Medtronic, Dublin, Ireland), the COMFORT Behavior, and the modified Face, Legs, Activity, Cry, Consolability Scale scores to predict patient responses following a noxious stimulus.