I am a
Home I AM A Search Login

Papers of the Week

2021 Mar 12

Cochrane Database Syst Rev


Biologics for chronic rhinosinusitis.


Chong L-Y, Piromchai P, Sharp S, Snidvongs K, Webster KE, Philpott C, Hopkins C, Burton MJ
Cochrane Database Syst Rev. 2021 Mar 12; 3:CD013513.
PMID: 33710614.


This living systematic review is one of several Cochrane Reviews evaluating the medical management of patients with chronic rhinosinusitis. Chronic rhinosinusitis is common. It is characterised by inflammation of the nasal and sinus linings, nasal blockage, rhinorrhoea, facial pressure/pain and loss of sense of smell. It occurs with or without nasal polyps.   'Biologics' are medicinal products produced by a biological process. Monoclonal antibodies are one type, already evaluated in other inflammatory conditions (e.g. asthma and atopic dermatitis).