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Papers of the Week

Papers: 6 Mar 2021 - 12 Mar 2021

2021 Mar 02

Trends Immunol

When Eating Becomes a Pain in the Gut.


Adair T, Belz GT
Trends Immunol. 2021 Mar 02.
PMID: 33674226.


Irritable bowel syndrome often appears following gastrointestinal infection and is marked by diarrhea, dysbiosis, fever, and intestinal pain following eating. A recent study by Aguilera-Lizarraga et al. now demonstrates that a breakdown in intestinal immunotolerance sparks an inflammatory response to typically tolerated food antigens and causes visceral pain.