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2021 Mar 06


Pharmacoepidemiol Drug Saf

Women are started on a lower daily dose of metoprolol than men irrespective of dose recommendations.

Authors

Hendriksen LC, Verhamme KMC, Van der Linden PD, Stricker BH, Visser LE
Pharmacoepidemiol Drug Saf. 2021 Mar 06.
PMID: 33675258.

Abstract

Current guidelines have no sex-specific dosage advice for metoprolol. To evaluate whether women and men are prescribed the same dose a cohort analysis was performed in the population-based Rotterdam Study (RS). Results were replicated in the Integrated Primary Care Information (IPCI) database of automated general practice data.