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Papers of the Week

2018 Jul 01

J Appl Lab Med



Clinical Use and Monitoring of Antiepileptic Drugs.


Knezevic CE, Marzinke MA
J Appl Lab Med. 2018 Jul 01; 3(1):115-127.
PMID: 33626819.


Antiepileptic drugs (AEDs) have been used for the treatment of epilepsy and other neurological disorders since the late 19th century. There are currently several classes of AEDs available for epilepsy management, many of which are also used to treat migraines, bipolar disorder, schizophrenia, depression, and neuropathic pain. Because of their molecular and mechanistic diversity, as well as the potential for drug-drug interactions, AEDs are prescribed and monitored in a highly personalized manner.