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Papers of the Week

2021 Jan 15

Ann Surg

Intravenous Local Anesthetic Compared with Intraperitoneal Local Anesthetic in Laparoscopic Colectomy: A Double-Blind Randomized Controlled Trial.


MacFater WS, Xia W, Barazanchi AWH, Lightfoot NJ, Weston M, Svirskis D, Hill AG
Ann Surg. 2021 Jan 15.
PMID: 33630453.


Controlling perioperative pain is essential to improving patient experience and satisfaction following surgery. Traditionally opioids have been frequently utilised for postoperative analgesia. Although they are effective at controlling pain, they are associated with adverse effects, including postoperative nausea, vomiting, ileus and long-term opioid dependency.Following laparoscopic colectomy, the use of intravenous or intraperitoneal infusions of lidocaine (IVL, IPL) are promising emerging analgesic options. Although both techniques are promising, there have been no direct, prospective randomized comparisons in patients undergoing laparoscopic colon resection. The purpose of this study was to compare IPL with IVL.