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Papers of the Week

Papers: 20 Feb 2021 - 26 Feb 2021

Human Studies, Pharmacology/Drug Development

2021 Feb 24

Pain Med

Reward Responsiveness in Patients with Opioid Use Disorder on Opioid Agonist Treatment: Role of Comorbid Chronic Pain.


Finan PH, Letzen J, Epstein DH, Mun C J, Stull S, Kowalczyk WJ, Agage D, Phillips KA, Pizzagalli DA, Preston KL
Pain Med. 2021 Feb 24.
PMID: 33624802.


Evidence suggests that blunted reward responsiveness may account for poor clinical outcomes in both opioid use disorder (OUD) and chronic pain. Understanding how individuals with OUD and comorbid chronic pain (OUD+CP) respond to rewards is, therefore, of clinical interest because it may reveal a potential point of behavioral intervention.