I am a
Home I AM A Search Login

Papers of the Week

Papers: 20 Feb 2021 - 26 Feb 2021

Animal Studies, Pharmacology/Drug Development

2021 Feb 13

Drug Alcohol Depend


Repeated morphine exposure activates synaptogenesis and other neuroplasticity-related gene networks in the dorsomedial prefrontal cortex of male and female rats.


Liu SX, Gades MS, Swain Y, Ramakrishnan A, Harris AC, Tran PV, Gewirtz JC
Drug Alcohol Depend. 2021 Feb 13; 221:108598.
PMID: 33626484.


Opioid abuse is a chronic disorder likely involving stable neuroplastic modifications. While a number of molecules contributing to these changes have been identified, the broader spectrum of genes and gene networks that are affected by repeated opioid administration remain understudied.