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Papers of the Week

2021 Feb 17

J Ethnopharmacol

Evaluation of Virola oleifera activity in musculoskeletal pathologies: inhibition of human multiple myeloma cells proliferation and combination therapy with dexamethasone or bortezomib.


Francisco V, Ruiz-Fernández C, González-Rodríguez M, Cordero-Barreal A, Pino J, Viñuela JE, Lago F, Conde J, Gómez R, Rocha Carvalho G, Melo Costa Pereira T, Campos-Toimil M, Gualillo O
J Ethnopharmacol. 2021 Feb 17:113932.
PMID: 33609728.


Virola oleifera (Schott) A.C. Smith, Myristicaceae, has been widely used in traditional medicine in Brazil to treat rheumatic pain, joint tumours, skin diseases, halitosis, bronchial asthma, haemorrhoids, and intestinal worms. Recently, research data showed the antioxidant properties in several oxidative stress-related models. However, there is no experimental evidence supporting its potential use in managing rheumatic diseases and bone malignancies.