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Papers of the Week

2021 Feb 18

Adv Rheumatol



Correlating cognition and cortical excitability with pain in fibromyalgia: a case control study.


Tiwari V K, Nanda S, Arya S, Kumar U, Sharma R, Kumaran SS, Bhatia R
Adv Rheumatol. 2021 Feb 18; 61(1):10.
PMID: 33602339.


Fibromyalgia is a chronic pain disorder characterized by widespread musculoskeletal symptoms, primarily attributed to sensitization of somatosensory system carrying pain. Few reports have investigated the impact of fibromyalgia symptoms on cognition, corticomotor excitability, sleepiness, and the sleep quality – all of which can deteriorate the quality of life in fibromyalgia. However, the existing reports are underpowered and have conflicting directions of findings, limiting their generalizability. Therefore, the present study was designed to compare measures of cognition, corticomotor excitability, sleepiness, and sleep quality using standardized instruments in the recruited patients of fibromyalgia with pain-free controls.