I am a
Home I AM A Search Login

Papers of the Week


2021 Mar


eNeurologicalSci


22

Detect it so you can treat it: A case series and proposed checklist to detect neurotoxicity in checkpoint therapy.

Authors

Bolz S, Ramakrishnan T, Fleischer M, Livingstone E, Stolte B, Thimm A, Kizina K, Ugurel S, Kleinschnitz C, Glas M, Zimmer L, Hagenacker T
eNeurologicalSci. 2021 Mar; 22:100324.
PMID: 33604462.

Abstract

Checkpoint inhibitors show impressive and durable responses in various cancer types and provide new avenues for cancer immunotherapy. However, these drugs have a variety of adverse events. Common autoimmune-related adverse effects include fatigue, hepatitis, skin rash, endocrine deficiencies, and colitis. Neurotoxicity has been reported, but its incidence and course remain unclear.