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Papers of the Week

2021 Feb 19

Neurourol Urodyn

Beneficial effect of Bletilla striata extract solution on zymosan-induced interstitial cystitis in rat.


Liu Y-C, Lee W-T, Liang C-C, Lo T-S, Hsieh W-C, Lin Y-H
Neurourol Urodyn. 2021 Feb 19.
PMID: 33604897.


Interstitial cystitis (IC) is a chronic pain syndrome that is characterized by suprapubic pain upon bladder filling. Bletilla striata, a well-known traditional Chinese herb with established efficacy in wound healing and anti-inflammation, was hypothesized to improve the symptoms of IC possibly though forming a physical barrier that could isolate the bladder tissue from irritants. This study was conducted to evaluate the beneficial effects of intravesical treatment with B. striata extract solution (BSES) on visceral pain and bladder function of rats with zymosan-induced IC.