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Papers of the Week

Papers: 6 Feb 2021 - 12 Feb 2021

Human Studies, Pharmacology/Drug Development


2021 Feb 10

Clin Pharmacokinet

Pharmacokinetics, Safety, and Tolerability of Lasmiditan in Pediatric Patients with Migraine.


Tsai M, Nery E S M, Kerr L, Khanna R, Komori M, Dennehy EB, Wilbraham D, Winner P
Clin Pharmacokinet. 2021 Feb 10.
PMID: 33565026.


Lasmiditan is a selective serotonin (5-HT1F) receptor agonist approved in the US for the acute treatment ofmigraine in adults. This phase I, open-label, two-cohort study assessed the pharmacokinetics (PK), safety, and tolerability of lasmiditan in patients with migraine aged 6 to < 18 years.