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Papers of the Week


2021


PLoS One


16


2

The adverse effects of bisphosphonates in breast cancer: A systematic review and network meta-analysis.

Authors

Jackson C, Freeman ALJ, Szlamka Z, Spiegelhalter DJ
PLoS One. 2021; 16(2):e0246441.
PMID: 33544765.

Abstract

Bisphosphonate drugs can be used to improve the outcomes of women with breast cancer. Whilst many meta-analyses have quantified their potential benefits for patients, attempts at comprehensive quantification of potential adverse effects have been limited. We undertook a meta-analysis with novel methodology to identify and quantify these adverse effects.