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Papers of the Week


2021 Feb 05


Eur J Drug Metab Pharmacokinet

Pharmacokinetics of Morphine and Morphine-6-Glucuronide During Postoperative Pain Therapy in Cardiac Surgery Patients.

Authors

Ihmsen H, Schüttler J, Jeleazcov C
Eur J Drug Metab Pharmacokinet. 2021 Feb 05.
PMID: 33547559.

Abstract

Morphine is a standard analgesic drug for postoperative pain therapy. This study aimed to evaluate the pharmacokinetics of morphine and its active metabolite morphine-6-glucuronide (M6G) in cardiac surgery  patients during postoperative analgesia.