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Papers of the Week


2021 Feb 06


Eur Spine J

Measurement of vertebral endplate bone marrow lesion (Modic change) composition with water-fat MRI and relationship to patient-reported outcome measures.

Authors

Fields AJ, Ballatori A, Han M, Bailey JF, McCormick ZL, O'Neill CW, Demir-Deviren S, Krug R, Lotz JC
Eur Spine J. 2021 Feb 06.
PMID: 33547944.

Abstract

Vertebral endplate bone marrow lesions ("Modic changes", MC) are associated with chronic low back pain (CLBP). Bone marrow composition in MC is poorly understood. The goals of this study were to: (1) measure bone marrow fat fraction (BMF) in CLBP patients with MC using water-fat MRI and (2) assess the relationship between BMF measurements and patient-reported clinical characteristics.