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Papers of the Week

Papers: 30 Jan 2021 - 5 Feb 2021

Human Studies

2021 Feb 03

Eur J Pain

The effect of acute-experimental pain models on offset analgesia.


Szikszay TM, Adamczyk WM, Hoegner A, Woermann N, Luedtke K
Eur J Pain. 2021 Feb 03.
PMID: 33533139.


Offset analgesia (OA) is characterized by a disproportionately large decrease in pain perception after a slight decrease in noxious stimulation. In patients with ongoing pain, this response is reduced. The effect is pronounced in painful body areas. The influence of acute pain has not been sufficiently investigated. The aim of this study was to investigate the influence of two experimental acute pain models, measured within the area of acute pain and on the non-affected opposite side, thereby considering the possible somatotopic nature of OA.