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Papers of the Week

Papers: 30 Jan 2021 - 5 Feb 2021

Animal Studies


2021 Feb 01


TRESK background potassium channel modifies the TRPV1-mediated nociceptor excitability in sensory neurons.


Lengyel M, Hajdu D, Dobolyi A, Rosta J, Czirják G, Dux M, Enyedi P
Cephalalgia. 2021 Feb 01:333102421989261.
PMID: 33525904.


TWIK-related spinal cord potassium channel (TRESK) background potassium channels have a key role in controlling resting membrane potential and excitability of sensory neurons. A frameshift mutation leading to complete loss of TRESK function has been identified in members of a family suffering from migraine with aura. In the present study, we examined the role of TRESK channels on nociceptor function in mice.