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Papers of the Week

2021 Jan 25

J Ethnopharmacol

Antinociceptive and anti-inflammatory activities of Copaifera pubiflora Benth oleoresin and its major metabolite ent-hardwickiic acid.


Símaro G V, Lemos M, da Silva J J M, Ribeiro V P, Arruda C, Schneider A H, Wagner de Souza Wanderley C, Carneiro L J, Mariano R L, Ambrósio S R, de Andrade S F, Banderó-Filho VC, Sasse A, Sheridan H, Silva M L AE, Bastos J K
J Ethnopharmacol. 2021 Jan 25:113883.
PMID: 33508366.


Copaifera species folkloric names are "copaíbas, copaibeiras, copaívas or oil stick", which are widely used in Brazilian folk medicine. Among all ethnopharmacological applications described for Copaifera spp oleoresins, their anti-inflammatory effect stands out. However, the knowledge of anti-inflammatory and antinociceptive properties of Copaifera pubiflora Benth is scarce.