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Papers of the Week


2021 Jan 11


World Neurosurg

Treatment Outcomes of Intracranial Myeloid Sarcomas: A Meta-Analysis.

Authors

Lee D, Omofoye OA, Nuño MA, Riestenberg RA, Shahlaie K
World Neurosurg. 2021 Jan 11.
PMID: 33444829.

Abstract

Intracranial myeloid sarcomas (IMS) are rare CNS manifestations of malignant hematopoietic neoplasms of myeloid origin such as AML and CML. Reported cases in the literature are limited to primarily case reports. We present a systematic review of this rare CNS tumor, characterizing the clinical presentation, tumor location, histopathology, and available treatment modalities. We correlate these variables with mortality, recurrence, and complications to suggest optimal management strategies for IMS.