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Papers: 16 Jan 2021 - 22 Jan 2021
Human Studies, Pharmacology/Drug Development
2021 Jan 12
J Clin Med
10
2
Activation of TRPM8, a cold-sensing receptor located on the cornea and eyelid, has the potential to relieve the neuropathic ocular pain (NOP) in dry eye (DE) by inhibiting other aberrant nociceptive inputs. We aimed to investigate the effect of a topical TRPM8 agonist, cryosim-3 (C3), on relieving DE-associated NOP.