I am a
Home I AM A Search Login

Papers of the Week

Papers: 2 Jan 2021 - 8 Jan 2021

Pharmacology/Drug Development

2020 Dec 28

Clin Neurol Neurosurg


The analgesic effect of intravenous lidocaine versus intrawound or epidural bupivacaine for postoperative opioid reduction in spine surgery: A systematic review and meta-analysis.


Tsai S H L, Yolcu Y U, Hung S-W, Kurian SJ, Alvi M A, Fu T-S, Bydon M
Clin Neurol Neurosurg. 2020 Dec 28; 201:106438.
PMID: 33385933.


Pain management following spine surgery remains a challenge. The significant use of opioids may lead to opioid-related adverse events. These complications can increase perioperative morbidity and rapidly expend health care resources by developing chronic pain. Although intraoperative pain control for surgery has been studied in the literature, a thorough assessment of the effect in spine surgery is rarely reported. The objective of the present study was to examine the outcomes of intraoperative intravenous lidocaine and intrawound or epidural bupivacaine use in spine surgery.